Frontline Plus Large Dog 20–40 Kg (3’s) | Powerful Flea & Tick Protection

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Monthly tick and flea treatment for large dogs, using fipronil and (S)-methoprene to kill parasites and break the flea life cycle.

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  • Product Details
  • Key Benefits
  • Usage & Ingredients
  • FAQs & Care Tips

Frontline Plus Large Dog (20–40 kg)

When your “lap dog” weighs as much as a small human, parasite protection needs to be serious business.
Frontline Plus Large Dog (20–40 kg) is designed for dogs that live big, roam far, and attract fleas
and ticks like it’s a competitive sport. This is a trusted tick and flea treatment for dogs across South Africa,
offering fast-acting, waterproof protection without unnecessary complexity.

Large dogs naturally spend more time outdoors — brushing through grass, rolling in gardens, and exploring spaces
where ticks and fleas thrive. That makes them prime targets for infestations.
Frontline Plus doesn’t just deal with what’s visible; it shuts down the flea life cycle before your home becomes
a secondary parasite habitat.

Built on proven veterinary science rather than trends, Frontline Plus Large Dog (20–40 kg) uses a dual-action
approach that works consistently in South Africa’s warm, parasite-friendly climate.
No guesswork, no rotating schedules — just monthly protection that fits real life.

Learn more about how Frontline Plus works directly from the manufacturer:

Official Frontline Plus Product Information

Key Benefits for Big Dogs

Frontline Plus Large Dog (20–40 kg) delivers full-spectrum parasite control without overcomplicating your routine.
Its benefits are designed around consistency, safety, and long-term effectiveness.

  • Kills adult fleas rapidly and ticks within hours.
  • Breaks the flea life cycle by stopping eggs, larvae, and pupae.
  • Water-resistant once dry — remains effective after baths or rain.
  • Provides up to 30 days of protection per application.
  • Helps control Flea Allergy Dermatitis (FAD) and biting lice.
  • Formulated specifically for dogs weighing 20–40 kg.
Biksie Insight:
Only around 5% of fleas live on your dog. The rest hide in carpets, bedding, furniture, and car seats.
Products that break the flea life cycle are what stop infestations from coming back.

For large dogs with active lifestyles, this level of protection keeps scratching, discomfort,
and parasite stress from becoming a constant issue.

How to Use & What’s Inside

Correct application ensures Frontline Plus performs exactly as intended.
Applying to fur instead of skin is the most common mistake — and the easiest way to reduce effectiveness.

  1. Remove the pipette from its packaging.
  2. Hold upright and snap off the tip.
  3. Part the fur between the shoulder blades until skin is visible.
  4. Apply the entire pipette directly onto the skin in one spot.
  5. Allow the area to dry before touching.

Dosage: One pipette per dog weighing 20–40 kg. Reapply every 30 days for continuous protection.

Active Ingredients

  • Fipronil (100 g/L): Eliminates adult fleas and ticks on contact.
  • (S)-Methoprene (90 g/L): Prevents flea eggs and larvae from developing.

This combination ensures both immediate parasite control and long-term prevention.

FAQs & Practical Care Tips

How long can ticks survive?

Ticks can live for years if they find hosts intermittently.
Consistent monthly prevention is the most effective way to manage risk.

Does Frontline Plus need fleas to bite?

No. Fipronil works on contact, killing fleas and ticks without requiring a bite.

Where do ticks come from?

Ticks thrive in tall grass, garden edges, and shaded outdoor areas.
Dogs pick them up during normal movement through these environments.

Pro Tip:
Wash bedding weekly and vacuum carpets regularly.
Parasite control works best when environmental hygiene supports treatment.

Some dogs become anxious during treatment.
Applying Frontline Plus after exercise, when your dog is relaxed, often makes the process easier.

Frontline Plus Large Dog (20–40 kg) delivers dependable, science-backed flea and tick protection
for dogs that live life at full size. Simple to apply, tough on parasites, and trusted across South Africa —
because big dogs deserve protection that keeps up.

Reviews

  1. 5 out of 5

    Biksie Team

    Frontline Plus Large Dog – Tick & Flea Treatment That Actually Works is a flea and tick control product we stock with confidence, selected for reliability and ease of use as part of regular care.

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Shipping policy

At our Biksie, we understand the importance of timely delivery. We offer a variety of shipping options to suit your needs, including standard, expedited, and express shipping. Our dedicated team works diligently to process and dispatch your orders promptly, aiming to deliver them to your doorstep within the estimated timeframe.

We strive to provide fast and reliable shipping to our customers. Here’s everything you need to know about our shipping process:

  • Orders are processed promptly and typically delivered within 3–5 business days, depending on your location.
  • Shipping fees are calculated at checkout based on your location and order size.
  • Free shipping applies to orders over R1000.
  • Delivery times may vary slightly due to courier schedules or high-demand periods.
  • Easy 7 day returns and exchanges

We work with trusted courier partners to ensure your parcel arrives safely and on time. Please note that delivery times are estimates and may vary depending on factors such as product availability, destination, and carrier delay.

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Returns policy

We want you to be completely satisfied with your purchase from our website. If for any reason you are not entirely happy with your order, we’re here to help. Certain exclusions and conditions may apply, so we encourage you to review our detailed return policy for more information. Rest assured, our goal is to ensure your complete satisfaction with every purchase you make from our website. See our Returns Policy.

  1. Returned items must be unused, undamaged, and in the same condition as received.
  2. Original tags, labels, and packaging must be intact and included with the returned item.
  3. Proof of purchase, such as your order confirmation or receipt, is required for all returns.